In prenatal medicine, screening protocols frequently rely on the integration of morphological ultrasound with non-invasive prenatal testing, which analyzes cell-free fetal DNA circulating in maternal blood to estimate the risk of chromosomal abnormalities.

In high-risk pregnancies, the results of non-invasive prenatal testing are routinely interpreted alongside morphological ultrasound findings, reinforcing a multimodal approach to fetal assessment in which imaging and molecular data are mutually informative.