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immature oocyte at prophase I
An immature egg that is in the first meiotic division in which the nucleus, known as the germinal vesicle, is visible. 
Grammatical category Noun
Field Cell biology
Level of specialization High
Definition source glosario de Fertilidad
Starting age Between 12 and 18 years
Gender relationship Yes, woman
Specific to one sex Yes
Prevalence Woman
Variants
Synonym
germinal vesicle stage
Formal
GV-stage oocyte
Formal
Equivalents

Spanish

ovocito profase I

Valenciano

ovòcit profase I
Associated concepts
Type of
oocyte stage
Examples
In the germinal-vesicle stage, corresponding to the immature oocyte at prophase I, telomere integrity is essential for proper chromosomal pairing and subsequent embryonic competence. 
Disruption of thyroid hormone signaling during development may interfere with meiotic progression, increasing the persistence of immature oocytes at prophase I and thereby contributing to defective folliculogenesis and reduced reproductive competence in adulthood.