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gonadotoxicity
The capacity of certain agents, such as chemotherapy or radiotherapy, to induce functional or structural damage to the gonads. Also known as gonadal toxicity, it triggers a decline in ovarian reserve or spermatogenesis, leading to infertility.
Grammatical category Noun
Field Diagnostic tests
Level of specialization High
Definition source Propia
Variants
Synonym
gonadal toxicity
Formal
Equivalents

Spanish

gonadotoxicidad

Valenciano

gonadotoxicitat
Associated concepts
Caused by
radiation therapy and chemotherapy
alkylating agents
gonadotoxic treatment
May cause
premature ovarian insufficiency
azoospermia
infertility
follicle loss
reduced ovarian reserve
gonadal damage
Examples
Given the increased survival rates, there will be a growing number of female patients who will experience the undesired gonadotoxicity associated with oncologic treatments.
Gonadotoxicity depends on several factors such as the type and dose of chemotherapy or radiation, the type of cancer, and the age of the patient. 
Collocations
WITH ADJECTIVES
undesired || acute | chemotherapy-induced gonadotoxicity

WITH NOUNS
relevance of gonadotoxicity | extent of gonadotoxicity | degree of gonadotoxicity