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gonadotropin-releasing hormone agonist
A drug analogue of this hormone which,  after an initial phase of pituitary stimulation, desensitises the receptors for gonadotropin-releasing hormone (GnRH) and reduces the secretion of LH (luteinising hormone) and FSH (follicle-stimulating hormone). In assisted reproduction, it is used to control pituitary function and prevent premature ovulation during controlled ovarian stimulation. It is also known as GnRHa.
Grammatical category Noun
Field Anatomy, physiology and embryology
Level of specialization High
Definition source glosario de Fertilidad
Variants
Synonym
Formal
Abbreviation
Formal
Equivalents

Spanish

agonista de la hormona liberadora de gonadotropina
agonista de la GnRH

Valenciano

agonista de l'hormona alliberadora de gonadotropina
agonista de la GnRH
Associated concepts
Type of
medication
May cause
mood swings
hot flushes
headache
vaginal dryness
hypo-oestrogenic symptoms
functional ovarian cysts at the start of treatment
Causes
initial pituitary stimulation
desensitisation of GnRH receptors
reduced secretion of LH and FSH
functional ovarian suppression
Examples
Before initiating gonadotropin-releasing hormone agonists  solely or with GAH treatment, 25 adolescent transgender females were referred to FP in our Fertility Institute of a tertiary university-affiliated medical center.
As for the trigger, gonadotropin-releasing hormone agonist GnRH agonist 0.2mg/2ml and human chorionic gonadotropin (HCG )1500 IU were used.
Collocations
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iniciate gonadotropin-releasing hormone agonist